Interdisciplinary Biotechnology Unit
Dr. Hina Younus
|Qualification :||Ph.D in Biotechnology from A.M.U, Aligarh|
|Designation :||Associate Professor|
|Thrust Area :||Enzymology and Nanoparticle research|
|Address :||Interdisciplinary Biotechnology Unit, A.M.U, Aligarh-202002|
|Email :||firstname.lastname@example.org, email@example.com|
|Time Table :||Click to View|
My teaching interest is in Enzymology, Protein chemistry and Cell biology. My research revolves on various aspects of enzymes: Characterization of new enzyme activities, enzyme stabilization, glycation, modulators of enzyme activity. My current focus is on alcohol/aldehyde dehydrogenases, enzyme glycation and its protection by natural compounds and nanoparticles, and modulating enzymatic activity in the presence of nanoparticles, Laccases, Zeta crystallin and therapeutic potential of nanoparticles of natural compounds. I have worked with Prof. Renate Ulbrich-hofmann, Department of Biotechnology, Martin Luther university, Halle, Germany as a DAAD research fellow. I have done my postdoctorate from IUPUI, Indianapolis, U.S.A. And I have published 61 research papers in various peer review reputed journals including Nature Structural & Molecular Biology (IF: 13.3), Biochimica et Biophysica Acta (IF: 4.7), Chemosphere (IF: 5.1), etc. I have edited one book and contributed 4 book chapters.
1. Perez-Miller, S., Younus, H., Vanam, R., Chen C.H., Mochly-Rosen, D., Hurley, T.D., Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant. Nature Structural & Molecular Biology 17 (2010) 159-165. IF: 13.3.
2. Khan M.A, Anwar S., Aljarbou A.N., Al-Orainy M., Aldebasi Y.H., Islam S., Younus H., Protective effect of thymoquinone on glucose or methylglyoxal-induced glycation of superoxide dismutase. Int. J. Biol. Macromol. 65 (2014) 16-20. IF: 4.8.
3. Laskar A.A., Khan M.A., Rahmani A.H., Fatima S., Younus H., Thymoquinone, an active constituent of Nigella sativa seeds, binds with bilirubin and protects mice from hyperbilirubinemia and cyclophosphamide-induced hepatotoxicity, Biochimie 127 (2016) 205-213. IF: 3.4
4. Laskar A.A., Khan M.A., Askari F., Younus H., Thymoquinone binds and activates human salivary aldehyde dehydrogenase: potential therapy for the mitigation of aldehyde toxicity and maintenance of oral health, Int. J. Biol. Macromol. 103 (2017) 99-110. IF: 4.8
5. Laskar A.A., Younus H. Aldehyde toxicity and metabolism: the role of aldehyde dehydrogenases in detoxification, drug resistance and carcinogenesis. Drug Metab. Rev. (2018) Dec 4:1-23. IF: 4.7