Interdisciplinary Biotechnology Unit
Prof. Rizwan Hasan Khan
|Qualification :||Ph.D.M.Phil.M.Sc.B. Sc|
|Thrust Area :||Protein structure, function,aggregation and amyloids|
|Address :||Int. Biotechnology Unit, AMU ,Aligarh: Permanent address:431/227 Katghar, Allahabad|
|Download :||Click here to download study materials|
Professor. Rizwan Hasan Khan has received his Ph.D. in Biotechnology from Aligarh Muslim University, Aligarh, India during the period of 1992-1996. Currently he is working in the area of protein structure, function , protein misfolding / aggregation and amyloid induction and inhibition at Aligarh Muslim University. He has published paper in journals like Biomacromolecules, Langmuir, PLoS ONE, Biochemistry, BBA, BBRC etc. He has worked with Prof. I.J.Goldstein at University of Michigan USA as BOYSCAST Fellow and with Prof. Steve Perkins at University of London as Commonwealth Fellow. He has guided 21 PhD thesis and completed 12 research projects. He had published around 295 papers in the journals of international repute with H index of 47 and total citation around 8844. His teaching interest is in the field of Biochemistry/Biotechnology for postgraduate.He is editor of several journals.
a. Gupta J, Hoque M, Zaman M, Khan RH, Saleemuddin M.(2016) A detergent-based procedure for the preparation of IgG-like bispecific antibodies in high yield. Sci Rep. 2016 Dec 16;6:39198. doi: 10.1038/srep39198
b. Alam P, Chaturvedi SK, Siddiqi MK, Rajpoot RK, Ajmal MR, Zaman M, Khan RH Vitamin k3 inhibits protein aggregation: Implication in the treatment of amyloid diseases. Sci Rep. 2016 May 27;6:26759. doi: 10.1038/srep26759
c. Khan JM, Abdulrehman SA, Zaidi KF, Gourinath S, Khan RH. Hydrophobicity alone cannot trigger aggregation in protonated mammalian serum albumins. Phys Chem Chem Phys (2014)16, 5150-5161
d. Khan J M, Chaturvedi S K, Rehman S K, Ishtikhar M, Qadeer A, Ahmed E and Khan R H. Protonation Favors aggregation of Lysozyme with SDS. Soft Matter, 2014, 10, 2591.
e. Laskar K, Alam P, Khan RH, Rauf A. Synthesis, characterization and interaction studies of 1,3,4-oxadiazole derivatives of fatty acid with human serum albumin (HSA): A combined multi-spectroscopic and molecular docking study Eur J Med Chem. 2016 Oct 21;122:72-8
f.Siddiqi MK, Alam P, Iqbal T, Majid N, Malik S, Nusrat S, Alam A, Ajmal MR, Uversky VN, Khan RH..Elucidating the Inhibitory Potential of Designed Peptides Against Amyloid Fibrillation and Amyloid Associated Cytotoxicity. Front Chem. 2018 Aug 3;6:311. doi: 10.3389/fchem.2018.00311. eCollection 2018