23-JAN-2016: The ADR Monitoring Centre, J N Medical College, Aligarh Muslim University has recently issued a notice against the intra-vitrieal use of Avastin (Bevacizumab injection) 100mg/4ml, 400mg/16ml vials in the treatment of eye disease. The notice states that the use of the drug is leading to loss of vision.
Dr Mohammad Nasiruddin, Co-Ordinator, ADR Monitoring Centre confirmed that the notice was issued following an alert-notice from the Directorate of General of Health Services, Centre Drug Standard Control Organization, FDA Bhawan, New Delhi.
"The drug is not approved in India for ophthalmic use by intra-vitrieal route," said Dr Nasiruddin.
He added that it is requested that drug should not be used in ophthalmology to avoid such Serious Adverse Effect as directed by Directorate of General of Health Services, CDSCO, Ministry of Health and family Welfare, Government of India.